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pentobarbital will minimize the extent or impact of methadone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital will lower the extent or effect of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Average CYP3A4 inducers could lower progestin conce

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